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What Is Argyria?

Medically Reviewed by Debra Jaliman, MD on January 26, 2022

Argyria is a rare skin condition that can happen if silverish builds up in your torso over a long fourth dimension.

It can turn your peel, optics, internal organs, nails, and gums a blue-gray color, especially in areas of your body exposed to sunlight. That change in your skin color is permanent.

Symptoms

If you have argyria, the symptoms may start in your mouth, with your gums turning gray-brown. Your skin may starting time to turn slate-grayness, metallic, or blue-gray. This could happen after a few months or years, depending on how much argent you lot are exposed to. Information technology may only affect 1 area of skin, or information technology could alter the appearance of all your skin.

The discoloration may stand up out nearly on your forehead, olfactory organ, hands, and other areas that are exposed to the sun.

The whites of your eyes and nail beds may as well turn blue-gray.

Some people's internal organs in their abdomen -- such as the spleen, liver, and intestines -- accept on a bluish color, but y'all wouldn't know this unless you had surgery.

Causes

You might get argyria if you have dietary supplements that contain silver, use medication such as eyedrops or nose sprays that contain silver, or work where silver particles are in the air.

When y'all swallow argent, it corrodes in your breadbasket acid and turns into silverish common salt, which can travel through your bloodstream and end up in your skin. When exposed to sunlight, the silver salt turns dorsum to silver and colors your pare bluish. This is similar to the process silver goes through when used in blackness-and-white photography.

Colloidal silver. This dietary supplement tin cause argyria. Information technology consists of tiny silvery particles in a liquid. Makers of these products may claim they boost your immune system and can treat cancer, HIV and AIDS, shingles, herpes, and eye issues, but scientific research doesn't support that.

The FDA says over-the-counter drugs and supplements containing colloidal silver or silver salts aren't safe and effective. Silver has no known benefits when swallowed and isn't essential to the human being trunk.

Some drugs. If you take medication that contains silver for a long time, it tin can cause argyria. Luckily, those medicines aren't used as much as they used to be. The post-obit uses of silverish are among those that have been shown to crusade argyria:

• Silver nitrate used to treat gum bleeding and varicose veins
• Silver sulfadiazine foam used to prevent infection in wounds and burns
• Silverish acetate used in lozenges and other products to assistance quit smoking
• Colloidal silver protein used in eyedrops

On the job. People who piece of work with silvery for a long fourth dimension tin can go argyria. If y'all work in silver mining, processing, or manufacturing, or another field that brings you into regular contact with silver, yous may breathe in silvery particles or they may become lodged in your peel, causing argyria.

Other causes. Information technology's possible that some people's genes brand them more likely to get argyria.

There accept been rare cases of argyria caused past silvery-coated acupuncture needles, silver earrings, and dental pieces. Merely that'due south not likely to happen.

Diagnosis

If your doctor thinks you may have argyria, you'll become a physical exam and answer questions about your history and medications. Tell your doctor about any medications, dietary supplements, or treatments you've used that contain argent, and any other exposure to silver.

Your md may also do a skin biopsy -- taking a small amount of your skin for testing -- to confirm whether you have argyria.

Treatment

The peel discoloration that argyria causes won't go away. Only sunscreen can help prevent the color from darkening. Makeup tin can help hide the furnishings of argyria on your skin.

Using a five% hydroquinone handling on your skin may curb the amount of silver in your skin and make it wait better.

Light amplification by stimulated emission of radiation therapy may also help care for argyria.

Prevention

You tin prevent argyria by limiting your use of medications that contain silver and avoiding dietary supplements that contain argent.

If you're exposed to silvery or silver dust at work, check that your workplace follows the exposure limits gear up by the regime. The Occupational Rubber and Wellness Administration (OSHA) and the Mine Safety and Wellness Administration (MSHA) enforce a limit of 0.01 mg/m^three for metal and soluble argent compounds.

Source: https://www.webmd.com/skin-problems-and-treatments/argyria-overview

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